It's always been like this.
For as long as I can remember, I've been going to doctor appointments because of a hormone imbalance. I've never produced enough hormone, so I'm shorter, weaker, and more depressed than the other guys. My voice has always been higher, something I've been teased about in school. I had to take artificial hormones to start puberty. The patches I was given for that left me with scarring across my legs. Nobody but some of my immediate family knows about this.
Effects: I won't be able to have biological children and everything is much, much smaller than normal.